Sublingual Schwannoma: A Rare Case Report with Diagnostic and Surgical Challenges

Background: Schwannomas are solitary, slow-growing, benign tumors made of nerve sheath Schwann cells. Oral cavity involvement is rare, although around a quarter occur in the head and neck region. The patient in this publication is a 32-year-old woman who has a distinct, painless, slowly increasing swelling in her left sublingual area. Clinical presentation, FNAC, and contrast-enhanced CT were inconclusive. Complete surgical excision with enucleation and primary closure was performed. Definitive diagnosis was made by histology (Antoni A and B areas, Verocay bodies) and immunohistochemistry (S-100 positivity). The patient recovered uneventfully with no recurrence. Sublingual schwannoma, though rare, should be considered in differential diagnosis of floor-of-mouth swellings.

Keywords: Schwannoma, sublingual space, oral cavity, S-100, enucleation.