Study of Correlation Between Duration of Diabetes, atherogenic Index, and albuminuria in Type 2 Diabetic Subjects

A Manjula, Vinaya Siddalingappa Kotagi, Riyaz Ahmed, Madhu Kumar R
Author(s)
1Professor and Head, Department of General Medicine, Mysore Medical College and Research Institute, Mysore, India. 2Junior Resident, Department of General Medicine, Mysore Medical College and Research Institute, Mysore, India. 3Assistant Professor, Department of General Medicine, Mysore Medical College and Research Institute, Mysore, India.

Abstract

Background: Type 2 diabetes mellitus has emerged as one of the most significant non-communicable diseases of the present century, posing a sustained burden on healthcare systems worldwide. Objective: Study of Correlation Between Duration of Diabetes, atherogenic Index, and albuminuria In Type 2 Diabetic Subjects. Material and Methods: This cross-sectional, observational, analytical study was conducted in the outpatient department (OPD) and inpatient department (IPD) of the Department of General Medicine at K.R. Hospital, Mysore Medical College and Research Institute (MMCRI), Mysore. Results: The prevalence of microalbuminuria was high, indicating a considerable burden of early renal involvement among patients with type 2 diabetes mellitus. A statistically significant association was observed between duration of diabetes and the presence of microalbuminuria, demonstrating that patients with longer disease duration were more likely to develop early renal complications. Although HbA1c levels were slightly higher in patients with microalbuminuria, the association between glycaemic control and microalbuminuria was not statistically significant in this study. The atherogenic index of plasma (AIP) showed slightly higher mean values among patients with microalbuminuria, but the relationship did not reach statistical significance. Conclusion: Patients with longer disease duration had significantly higher prevalence of albuminuria, underscoring the cumulative effects of prolonged hyperglycaemia and metabolic stress on renal microvascular structures. Although the mean HbA1c levels and atherogenic index values were slightly higher among patients with microalbuminuria, these associations were not statistically significant in the present study.

Keywords: Duration of Diabetes, atherogenic Index, and albuminuria in T2 Diabetes Subjects.

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