A Clinical Study to Determine the Relation Between Hemoglobin A1c and Wound Healing in Diabetic Foot Wounds
Madhumitha V, N. Jeeva, P. Babu, P. Kannan, J. Karthick
Author(s)2Professor, Department of General Surgery, Government Mohan Kumaramangalam Medical College Hospital, Salem, Tamilnadu, India
3Assistant Professor, Department of General Surgery, Government Medical College and Hospital, Krishnagiri, Tamilnadu, India
4Assistant Professor, Department of General Surgery, Government Mohan Kumaramangalam Medical College Hospital, Salem, Tamilnadu, India
Abstract
Background: To test the hypothesis regarding the relation between HbA1c and diabetic foot wound healing, we conducted a prospective study of 200 diabetic foot ulcer patients treated at the Department of General Surgery, GMKMCH, Salem. Material and Methods: A prospective observational study analyzing clinical parameters, HbA1c levels, Wagner's grading, and surgical outcomes among 200 patients. Results: 72% were males and 28% females with ulcer duration >1 month. Neuropathic ulcers comprised 90% of cases, and amputation was performed in 41.5%. HbA1c > 6.5% was significantly associated with higher Wagner grades, BMI, retinopathy, nephropathy, hypertension, neuropathy, and smoking (p < 0.01). Conclusion: HbA1c demonstrates a strong linear relationship with Wagner's classification grades and predicts wound healing outcomes.
Keywords: Diabetic Foot Ulcer, Hemoglobin A1c, Wagner Grading, Wound Healing, Neuropathy, Amputation.